Among drugs belonging to the group of calcium antagonists, most commonly used Verapamil (Isoptin, finoptin) and nifedipine (korinfar). Verapamil has a moderate antiarrhythmic activity and preferably a combination of angina with cardiac arrhythmias. It is administered at a dose of 80 – 120 mg 3 – 4 times a day (Isoptin retard – 1 time per day), and 2-3 months after starting treatment dose can be gradually reduced, bringing it up to 160 – 120 grams per day.
Verapamil treatment in high doses requires electrocardiographic monitoring as possible inhibition of atrioventricular conduction. Nifedipine in a dose of 10 – 20 mg 3-4 times a day is the drug of choice in the treatment of spontaneous angina, in which nitro drugs are less effective, and the appointment of beta-blockers, according to some authors, is undesirable because of their possible promote the development of vasospasm.
When angina using a long-acting drug of the same group, amlodipine (Norvasc), which is prescribed by 5-10 mg per day.
As the anti-aggregation agent used is acetylsalicylic acid (aspirin), which use 1 to 0,125 g of once a day substantially reduces the risk of developing myocardial infarction patients.
Treatment of patients with progressive angina performed only in a hospital in a more rigorous than usual restriction of motor mode (load, causing angina, should be completely excluded).
Recommended split meals, diet containing digestible foods. It is important to follow the regular chair, if necessary, apply relaxant agents and enemas as straining during bowel movements often causes severe angina.